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Wei-Hwa Lee Selected Research

ovatodiolide

3/2019Ovatodiolide suppresses nasopharyngeal cancer by targeting stem cell-like population, inducing apoptosis, inhibiting EMT and dysregulating JAK/STAT signaling pathway.
9/2018Ovatodiolide suppresses yes-associated protein 1-modulated cancer stem cell phenotypes in highly malignant hepatocellular carcinoma and sensitizes cancer cells to chemotherapy in vitro.
1/2018Downregulation of Cancer Stemness by Novel Diterpenoid Ovatodiolide Inhibits Hepatic Cancer Stem Cell-Like Traits by Repressing Wnt/[Formula: see text]-Catenin Signaling.

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Wei-Hwa Lee Research Topics

Disease

49Neoplasms (Cancer)
10/2023 - 04/2003
12Hepatocellular Carcinoma (Hepatoma)
10/2023 - 01/2013
11Neoplasm Metastasis (Metastasis)
01/2022 - 07/2013
10Carcinogenesis
06/2021 - 07/2013
7Breast Neoplasms (Breast Cancer)
01/2022 - 07/2013
6Glioma (Gliomas)
08/2021 - 12/2009
5Squamous Cell Carcinoma of Head and Neck
01/2022 - 11/2015
5Colorectal Neoplasms (Colorectal Cancer)
08/2018 - 01/2006
4Inflammation (Inflammations)
03/2024 - 12/2005
4Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 12/2013
4Adenocarcinoma
01/2020 - 01/2006
4Glioblastoma (Glioblastoma Multiforme)
12/2018 - 05/2015
3Osteoarthritis
03/2024 - 10/2021
3Liver Neoplasms (Liver Cancer)
06/2021 - 01/2018
3Ovarian Neoplasms (Ovarian Cancer)
05/2017 - 05/2015
2Lung Neoplasms (Lung Cancer)
01/2019 - 12/2013
2Carcinoma (Carcinomatosis)
09/2018 - 05/2006
2Disease Progression
09/2018 - 02/2016
2Adenocarcinoma of Lung
01/2018 - 01/2018
2BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2018 - 01/2014
2Hyperglycemia
03/2015 - 12/2011
2Type 2 Diabetes Mellitus (MODY)
03/2015 - 12/2011
1Coronary Artery Disease (Coronary Atherosclerosis)
06/2022
1Arthritis (Polyarthritis)
10/2021
1Hypertrophy
10/2021
1Acquired Immunodeficiency Syndrome (AIDS)
06/2021
1Virus Diseases (Viral Diseases)
06/2021
1Colonic Neoplasms (Colon Cancer)
01/2021
1Plasmacytoma
01/2021
1Gliosarcoma
05/2020
1Hypoxia (Hypoxemia)
01/2020
1Esophageal Neoplasms (Esophageal Cancer)
12/2019

Drug/Important Bio-Agent (IBA)

9Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2006
7MicroRNAs (MicroRNA)IBA
03/2024 - 07/2013
6Cisplatin (Platino)FDA LinkGeneric
10/2021 - 01/2015
6CateninsIBA
01/2020 - 01/2013
5Biomarkers (Surrogate Marker)IBA
06/2022 - 01/2018
4pterostilbeneIBA
06/2015 - 01/2013
3Sorafenib (BAY 43-9006)FDA Link
02/2023 - 06/2021
3VimentinIBA
01/2022 - 12/2019
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2021 - 01/2006
3ovatodiolideIBA
03/2019 - 01/2018
34-acetylantroquinonol BIBA
12/2018 - 10/2015
3Tyrosine Kinase InhibitorsIBA
01/2018 - 01/2018
3Histone DemethylasesIBA
01/2018 - 01/2015
3Glucose (Dextrose)FDA LinkGeneric
09/2016 - 12/2011
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2024 - 10/2021
2Beclin-1IBA
02/2023 - 06/2021
2Hydroxychloroquine (Plaquenil)FDA LinkGeneric
02/2023 - 06/2021
2AntioxidantsIBA
01/2022 - 07/2017
2Therapeutic UsesIBA
10/2021 - 11/2015
2CytokinesIBA
10/2021 - 02/2014
2Agammaglobulinaemia Tyrosine KinaseIBA
02/2021 - 05/2015
2Long Noncoding RNAIBA
01/2021 - 02/2016
2Caspase 3 (Caspase-3)IBA
01/2020 - 10/2018
2PD 173074IBA
01/2020 - 10/2018
2CollagenIBA
06/2019 - 12/2005
2Messenger RNA (mRNA)IBA
01/2019 - 09/2016
2Imatinib Mesylate (Gleevec)FDA Link
01/2018 - 01/2014
2Facilitative Glucose Transport Proteins (Glucose Transporter)IBA
09/2016 - 03/2015
2Streptozocin (Streptozotocin)FDA Link
03/2015 - 12/2011
2osthol (osthole)IBA
03/2015 - 12/2011
2ErbB Receptors (EGF Receptor)IBA
12/2013 - 01/2006
2LipidsIBA
12/2011 - 01/2006
2Metalloproteases (Metalloproteinases)IBA
05/2006 - 01/2006
2Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA
05/2006 - 01/2006
1NF-kappa B (NF-kB)IBA
03/2024
1Reactive Oxygen Species (Oxygen Radicals)IBA
03/2024
1human MIRN-4282 microRNAIBA
03/2024
1notopterolIBA
03/2024
1InflammasomesIBA
03/2024
1InterleukinsIBA
03/2024
1Protein Phosphatase 1IBA
10/2023
1Growth Differentiation Factor 15IBA
06/2022
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
06/2022
1Mitogen-Activated Protein Kinase 14IBA
06/2022
1human ERBB2 proteinIBA
01/2022
1PlatinumIBA
01/2022
1Core Binding Factors (Core-Binding Factor)IBA
01/2022
1CalcineurinIBA
01/2022
1BX795IBA
10/2021
1tofacitinibIBA
10/2021
1Interleukin-6 (Interleukin 6)IBA
10/2021
1Janus Kinase InhibitorsIBA
10/2021
1acalabrutinibIBA
08/2021
1Sirolimus (Rapamycin)FDA Link
08/2021
1N- (cyanomethyl)- 4- (2- ((4- (4- morpholinyl)phenyl)amino)- 4- pyrimidinyl)benzamideIBA
06/2021
1EnzymesIBA
01/2021
1Protons (Proton)IBA
05/2020
1Firefly LuciferasesIBA
01/2020
1Untranslated RNA (Noncoding RNA)IBA
01/2020
1fatostatinIBA
12/2019
1Sterol Regulatory Element Binding Protein 1IBA
12/2019

Therapy/Procedure

13Therapeutics
10/2021 - 12/2013
9Drug Therapy (Chemotherapy)
01/2022 - 04/2003
4Radiotherapy
01/2020 - 01/2013
1Intra-Articular Injections
10/2021
1Chemoradiotherapy
02/2021
1Aftercare (After-Treatment)
05/2020
1Craniotomy
05/2020